2月份Science主刊揭橥了两篇背靠背文章,阐述粪便微生物移植废除黑色素瘤PD-1耐药。
1. Diwakar Davar et al,Fecal microbiota transplant overcomes resistance to anti-PD-1 therapy in melanoma patients,Science. 2021 Feb 5;371(6529):595-602.
2. Erez N Baruch et al,Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients,Science. 2021 Feb 5;371(6529):602-609.
(Oncogene https://doi.org/10.1038/s41388-020-1341-1)
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